Great Lakes Wire

The Michigan Department of Health and Human Services (MDHHS) has issued a warning regarding the significant rise in health emergencies linked to the recreational use of nitrous oxide, commonly known as "laughing gas," across the state. The Michigan Poison and Drug Information Center (MiPDC) reported a 533% increase in calls related to adverse effects from nitrous oxide use between 2019 and 2024. Emergency medical service responses saw a 553% rise, while emergency department visits surged by 757% from 2019 to 2023.

Dr. Natasha Bagdasarian, chief medical executive, expressed concern over these trends, stating, “The drug landscape is constantly changing and the increases in nitrous oxide misuse are concerning, given the widespread availability of the product and the increase in multiple substance use.” She emphasized the importance of awareness regarding the risks associated with chronic use.

Nitrous oxide is utilized medically as an anesthetic and analgesic but is also available commercially in whipped cream dispensers found online or at various retail outlets. It is often marketed to young people due to its availability in different flavors. Recreationally, it can induce euphoria and relaxation but poses serious health risks when used chronically.

Dr. Varun Vohra, MiPDC senior director and clinical toxicologist, highlighted this issue as a significant public health problem: “This is a serious public health problem. At the MiPDC, our consultants are encountering a significant increase in cases involving neurological and cardiovascular effects related to the recreational use of nitrous oxide.”

Chronic use can result in severe neurological damage and psychiatric issues such as weakness, numbness or tingling sensations, memory impairment, delusions, depression, mood changes, hypoxia (low oxygen levels), and even asphyxiation.

Those experiencing symptoms after using nitrous oxide should seek immediate medical attention. The MiDPC offers consultations through their hotline at 800-222-1222 for those needing more information or assistance from board-certified toxicologists.

Further details can be found in a recent Morbidity and Mortality Weekly Report publication.